Journal Articles
Our work in Journal Articles
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Measuring the COVID-19 Mortality Burden in the United States
A team from the USC Schaeffer Center undertook a full assessment of the first year of the pandemic’s mortality burden by measuring years of life lost and accounting for quality-of-life differences, factoring in age, sex, race/ethnicity and comorbidities.
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Cost-effectiveness of a Digital Health Intervention for Acute Myocardial Infarction Recovery
Acute myocardial infarction is a common cause of hospital admissions, readmissions, and mortality worldwide. Digital health interventions that promote self-management, adherence to guideline-directed therapy, and cardiovascular risk reduction may improve health outcomes in this population.
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Changes in Emergency Department Encounters for Vomiting After Cannabis Legalization in Colorado
Cannabis hyperemesis syndrome is an emerging clinical issue associated with cannabis use. Legalization of cannabis has led to an increase in vomiting-related illnesses in health care settings.
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Opioid-Related Deaths Before and After COVID-19 Stay-At-Home Orders in Los Angeles County
A new Schaeffer Center study partnered with the LA County Medical Examiner-Coroner’s Office to investigate whether the stay-at-home orders impacted opioid-related fatal overdoses.
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The Relationship Between States’ Staffing Regulations And Hospitalizations Of Assisted Living Residents
Assisted living provides housing and long-term care services to more than 811,000 older adults in the United States daily and is regulated by the states.
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Citizenship Status and Mortality Among Latinos: Analyses of the US National Health Interview Survey Linked Mortality Files
Forty million Latino adults reside in the United States, including eleven million who do not possess US citizenship. Noncitizens disproportionately experience poverty, segregation, and inadequate access to healthcare—pathogenic mechanisms that adversely impact health.
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A Guide to Extending and Implementing Generalized Risk‑Adjusted Cost‑Effectiveness
The generalized risk-adjusted cost-effectiveness (GRACE) model generalizes conventional cost-effectiveness analysis (CEA) by introducing diminishing returns to Health-Related Quality of Life (QoL).
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Generalized Risk-Adjusted Cost-Effectiveness (GRACE): Ensuring Patient-Centered Outcomes in Healthcare Decision Making
GRACE complements and adds to our previous analyses demonstrating how best to incorporate uncertain health benefits into value analyses.
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Lower-Risk Cannabis Use Guidelines (LRCUG) for Reducing Health Harms From Non-Medical Cannabis Use: A Comprehensive Evidence and Recommendations Update
Cannabis use is common, especially among young people, and is associated with risks for various health harms. Some jurisdictions have recently moved to legalization/regulation pursuing public health goals. Evidence-based ‘Lower Risk Cannabis Use Guidelines’ (LRCUG) and recommendations were previously developed to reduce modifiable risk factors of cannabis-related adverse health outcomes; related evidence has evolved substantially since.
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Prevalence and Distribution of High-Risk Prescription Opioid Use in the United States, 2011–2016
Abstract Purpose Despite the efforts of many stakeholders to reduce the risk of opioid overdose, there is limited information on the prevalence of high-risk prescription opioid use in the US. Methods Descriptive analysis of a nationally representative 5% random sample of anonymized, longitudinal, individual-level prescription claims from IQVIA LRx between January 1, 2011 and December […]
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