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Context Matters: Using an Evidence to Decision (EtD) Framework to Develop and Encourage Uptake of Opioid Deprescribing Guideline Recommendations at the Point-Of-Care
The context within which evidence-based recommendations are considered, as well the political and health-system environment, can contribute to the success of recommendation implementation.
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Estimating the Value of Repositioning Timing to Streamline Pressure Injury Prevention Efforts in Nursing Homes: A Cost-Effectiveness Analysis of the ‘TEAM-UP’ Clinical Trial
Abstract Pressure injury (PrI) prevention guidelines recommend 2-h repositioning intervals in healthcare settings, requiring significant nursing time investment. We analysed the cost-effectiveness of PrI prevention protocols with 2-, 3- and 4-h repositioning intervals in US nursing homes according to ‘Turn Everyone and Move for Ulcer Prevention’ (TEAM-UP) randomized controlled trial findings. Markov modelling compared 2-, […]
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Parental Divorce in Childhood and the Accelerated Epigenetic Aging for Earlier and Later Cohorts: Role of Mediators of Chronic Depressive Symptoms, Education, Smoking, Obesity, and Own Marital Disruption
Social and environmental contexts can shape these influences over time.
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The Impact of the Global COVID-19 Vaccination Campaign on All-Cause Mortality
A working paper from the USC Schaeffer Center and Brown University found the global vaccine campaign among 141 countries saved 2.4 million lives from January 2021 to August 2021. The study estimates 670,000 more lives would have been saved if COVID-19 vaccine distribution was more equitable.
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ADDITIONAL JOURNAL ARTICLES
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Race, Gender, and Cohort Differences in the Educational Experiences of Black and White Americans
Among White adults, many of the gender differences in educational experiences documented in the oldest cohort were still found among the most recent cohort; Most race inequities in educational experiences persiste
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Understanding Over- and Under-Screening of Cervical Cancer Among a National Sample of Commercially Insured Women: Implications for Health Equity
The study identified high rates of over-screening and under-screening among a national cohort of commercially insured women, signaling the need for interventions to improve guideline adherent screening
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Causes and Costs of Global COVID-19 Vaccine Inequity
The main contributors to vaccine inequity include vaccine nationalism, intellectual property rights, constraints in manufacturing capacity, poor resilience of healthcare systems, and vaccine hesitancy.
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Immune Cells Are Associated with Mortality: the Health and Retirement Study
The research findings support the idea that an aging immune system is associated with short-term mortality independent of age-related inflammation or other age-related measures of physiological dysfunction.
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Wellness Tour for Tribal Communities During the COVID-19 Pandemic: Uniting Sacred Space with Western Medicine to Prevent Substance Use
Substance use disorders (SUD) and overdose deaths worsened further during the Covid-19 pandemic in American Indian and Alaska Native (AIAN) communities.
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Eligibility Rates among Racially and Ethnically Diverse US Participants in Phase 2 and Phase 3 Placebo-Controlled, Double-Blind, Randomized Trials of Lecanemab and Elenbecestat in Early Alzheimer Disease
Differential eligibility may contribute to underrepresentation of some minoritized racial and ethnic groups in early AD trials. Amyloid biomarker eligibility is a requirement to confirm the diagnosis of AD and for treatment with amyloid-lowering drugs and differed among racial and ethnic groups.