Research

Abstract Neurosteroids, steroids synthesized in the nervous system, have important functions in modulating brain function, neuroprotection, and reducing neuroinflammation. The neurosteroid pregnenolone, the precursor to all other neurosteroids, is one of the most abundant neurosteroids in the brain. Still, the enzyme known to make it, CYP11A1, has been difficult to detect in the human brain. […]

Rates of cannabis-related hospitalizations declined immediately after legalization during a period of legal market immaturity and later increased during a period of legal market expansion and the COVID-19 pandemic.

The age-adjusted mortality rate (AAMR) of falls among adults aged 65 years or older rose nationally from 29.4 to 69.4 per 100,000 from 1999 to 2020.

Weekly PrEP use declined during the COVID-19 pandemic in 2020, with only 1 in 12 persons at high risk for HIV taking PrEP at least once a week by November 2020 in the U.S.

This study can help researchers better consider the full consequences of policy changes and help members of the media identify the dynamics of interactions that deserve more attention.

Using a patient’s self-defined goals can be a powerful motivator for improving health outcomes.

The increase in care use leading up to a dementia diagnosis is higher among beneficiaries in traditional Medicare than in Advantage plans and remains higher after diagnosis.

Of people appointed to the Department of Health and Human Services between 2004 and 2020, 15 percent had been employed in private industry immediately before their appointment.

More Black women received radiation therapy following breast-conserving surgery

nPEP use increased from 2010 to 2019, but not equally across all risk groups. Further policy interventions should be developed to reduce barriers and ensure adequate access to this important HIV prevention tool.