The OxyContin reformulation led some users of the drug to switch to heroin, which could have exposed them to the hepatitis C virus.
Supply-side interventions which limit access to opioids may have the unintended consequence of increasing use of substitute drugs, including heroin.
In light of the changing opioid problem, as well as the unprecedented duration of it, it seems critical to re‐assess strategies for solving the current epidemic.
The findings suggest that broader access to medical marijuana facilitates substitution of marijuana for powerful and addictive opioids.
This study describes the main theories explaining the explosion in opioid misuse in the United States as well as the primary public and private policies that have been attempted to reduce the supply, demand, and harms.